It is possible for the nail to become thicker, making it more difficult to care for. Given all of these details, Kerassentials can be regarded as one of the most secure products with strong antifungal properties. Our office uses an oil-based, skin-friendly medication that is safe and easy to use. People with chronic conditions like diabetes, heart disease, or immunodeficiency diseases are more likely to get fungal nails. This tends to be more effective than just the topical medication, though it takes a long time and doesn't work for everyone. This can cause discoloration, thickening and even complete loss of the nail plate. It can affect as many at 35 million people in America, but toenail problems are particularly common.